Wigan Warriors and Catalans Dragons play each other on Thursday with the hope of boosting their top four chances.
The sides currently lie second and third respectively, but with the league being decided on points percentage, any loss could see them fall behind.
The pair met in the first game in the south of France since lockdown, with the Warriors coming out on top.
It will kick off at 5.30pm.
Wigan make two changes to the side that beat Warrington Wolves last time out.
They are boosted by the returns of Ben Flower and Tony Clubb. Clubb has not played since lockdown because of a neck injury.
Harry Rushton and James McDonnell are the ones to drop out.
Catalans also make two changes, with Samisoni Langi and Remi Casty both picking up injuries in the win over Hull KR.
Replacing them are Matt Whitley and Arthur Romano, who were the two to drop out last week.