Table
| Position | Team | Played | Won | Draw | Loss | Points For | Points Against | Points Difference | Win Percentage |
| 1 | Toulouse | 6 | 6 | 0 | 0 | 291 | 58 | 501.72 | 100 |
| 2 | Featherstone Rovers | 7 | 7 | 0 | 0 | 258 | 76 | 344.74 | 100 |
| 3 | Bradford Bulls | 8 | 7 | 0 | 1 | 228 | 172 | 132.56 | 87.5 |
| 4 | Batley Bulldogs | 7 | 5 | 0 | 2 | 204 | 140 | 145.71 | 71.43 |
| 5 | London Broncos | 8 | 4 | 1 | 3 | 200 | 194 | 103.09 | 56.25 |
| 6 | Halifax Panthers | 8 | 4 | 0 | 4 | 241 | 129 | 186.82 | 50 |
| 7 | York City Knights | 8 | 4 | 0 | 4 | 213 | 150 | 142 | 50 |
| 8 | Widnes Vikings | 8 | 3 | 1 | 4 | 204 | 239 | 85.36 | 43.75 |
| 9 | Dewsbury Rams | 7 | 3 | 0 | 4 | 103 | 171 | 60.23 | 42.86 |
| 10 | Sheffield Eagles | 8 | 2 | 2 | 4 | 179 | 221 | 81 | 37.5 |
| 11 | Whitehaven | 8 | 2 | 1 | 5 | 140 | 254 | 55.12 | 31.25 |
| 12 | Oldham | 8 | 2 | 0 | 6 | 106 | 296 | 35.81 | 25 |
| 13 | Newcastle Thunder | 7 | 1 | 1 | 5 | 132 | 216 | 61.11 | 21.43 |
| 14 | Swinton Lions | 8 | 0 | 0 | 8 | 122 | 309 | 39.48 | 0 |
Friday 2nd April 2021
Featherstone Rovers 28-18 Batley Bulldogs
Halifax Panthers 47-14 London Broncos
Saturday 3rd April 2021
York City Knights 6-21 Toulouse
Sunday 4th April 2021
Newcastle Thunder 30-30 Widnes Vikings
Sheffield Eagles 50-12 Bradford Bulls
Saturday 17th April 2021
Widnes Vikings 14-22 Dewsbury Rams
Sunday 18th April 2021
Swinton Lions 6-36 Featherstone Rovers
Whitehaven 29-20 Newcastle Thunder
Bradford Bulls 27-26 Halifax Panthers
York City Knights 14-20 Sheffield Eagles
Saturday 24th April 2021
Batley Bulldogs 48-16 Widnes Vikings
Sunday 25th April 2021
Swinton Lions 16-64 York City Knights
Featherstone Rovers 48-14 Whitehaven
Halifax Panthers 34-44 Toulouse
Newcastle Thunder 24-16 Sheffield Eagles
Bradford Bulls 35-14 Dewsbury Rams
Saturday 1st May 2021
Sheffield Eagles 20-20 London Broncos
Sunday 2nd May 2021
Newcastle Thunder 16-28 Batley Bulldogs
Whitehaven 22-30 Bradford Bulls
Widnes Vikings 46-10 Swinton Lions
Dewsbury Rams 20-30 York City Knights
Friday 7th May 2021
Sheffield Eagles 18-30 Batley Bulldogs
Saturday 8th May 2021
Sunday 9th May 2021
Swinton Lions 22-23 Bradford Bulls
London Broncos 50-30 Newcastle Thunder
Dewsbury Rams 0-36 Halifax Panthers
York City Knights 12-16 Featherstone Rovers
Saturday 15th May 2021
Batley Bulldogs 6-40 London Broncos
Saturday 16th May 2021
Halifax Panthers P-P Sheffield Eagles
Widnes Vikings 14-35 York City Knights
Monday 17th May 2021
Swinton Lions 18-20 Dewsbury Rams
Featherstone Rovers 68-0 Oldham
Saturday 22nd May 2021
Sunday 23rd May 2021
Dewsbury Rams P-P Batley Bulldogs
London Broncos 8-33 Bradford Bulls
Newcastle Thunder 0-32 Halifax Panthers
Widnes Vikings 44-6 Whitehaven
York City Knights 34-6 Oldham
Sheffield Eagles 18-50 Featherstone Rovers
Saturday 29th May 2021
Toulouse P-P Newcastle Thunder
Sunday 30th May 2021
Batley Bulldogs 26-12 Swinton Lions
Bradford Bulls 37-18 York City Knights
Halifax Panthers 8-16 Featherstone Rovers
London Broncos 30-10 Dewsbury Rams
Oldham 18-40 Widnes Vikings
Sheffield Eagles 25-25 Whitehaven
Sunday 6th June 2021
Bradford Bulls 31-12 Newcastle Thunder
Halifax Panthers 46-12 Sheffield Eagles